TCA SE is Anti-HAM!!
antiH- istamine(sedation
antiA - adrenergic properties- CVS SEs : orthostatic hypotension (most life
threatening),tachycardia,arrhythmias
antiM- muscarinic effects -dry mouth,constipation,urinary retention,blurred vision,tachycardia
others- weight gain
- lethal in overdose (!!one week supply of the drugs can be lethal in overdose,so assess your patient suicide risk 1st!)
- major COMPLICATIONS- 3C = convulsions,coma,cardiotoxicity
mainstay of treatment of TCA overdose is IV sodium bicarbonate.
antiH- istamine(sedation
antiA - adrenergic properties- CVS SEs : orthostatic hypotension (most life
threatening),tachycardia,arrhythmias
antiM- muscarinic effects -dry mouth,constipation,urinary retention,blurred vision,tachycardia
others- weight gain
- lethal in overdose (!!one week supply of the drugs can be lethal in overdose,so assess your patient suicide risk 1st!)
- major COMPLICATIONS- 3C = convulsions,coma,cardiotoxicity
mainstay of treatment of TCA overdose is IV sodium bicarbonate.
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