SEs of TCAs

TCA SE is Anti-HAM!!
antiH- istamine(sedation
antiA - adrenergic properties- CVS SEs : orthostatic hypotension (most life
                 threatening),tachycardia,arrhythmias
antiM- muscarinic effects -dry mouth,constipation,urinary retention,blurred vision,tachycardia

others- weight gain
         - lethal in overdose (!!one week supply of the drugs can be lethal in overdose,so assess your patient suicide risk 1st!)
         - major COMPLICATIONS- 3C = convulsions,coma,cardiotoxicity

mainstay of treatment of TCA overdose is IV sodium bicarbonate. 

schizophrenia

5As of negative symptoms:

1. anhedonia
2. affec(flat)
3. alogia (poverty of speech)
4. avolition(apathy)
5. attention(poor)

Major depression Episode

1. Sleep
2. interest
3. Guilt
4. Energy
5. Concentration
6. Appetite
7. Psychomotor activity
8. Suicidal Ideation

Lithium

Lithium SEs: 

1. Weight gain
2.  Tremor
3. GI disturbance
4. Fatigue
5. Arrythmias
6. seizures
7. Goitre/hypothyroidism
8. leucocytosis
9. coma
10. polyuria
11. polydipsia
12. alopecia
13. metallic taste

1.